名稱(chēng) | ICOSL/CHO IO細(xì)胞株 |
型號(hào) | CBP74068 |
報(bào)價(jià) | ![]() |
特點(diǎn) | ICOSL/CHO |
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電話(huà):4008750250
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地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
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藥靶細(xì)胞株 > 腫瘤免疫細(xì)胞株 > CBP74068ICOSL/CHO IO細(xì)胞株

- 詳細(xì)內(nèi)容
CBP74068 | |
I. Background | |
ICOSL is the Ligand for the T-cell-specific cell surface receptor ICOS. When engaged by the ICOSL, the ICOS initiates a costimulatory signal for T-cell proliferation and cytokine production. It also induces B-cell proliferation and differentiation into plasma cells. The ICOS/ICOSL is a major regulator of the adaptive immune responses and also plays an important role in mediating local tissue responses to inflammatory conditions. | |
II. Description | |
Recombinant CHO-K1 cells constitutively expressing human ICOSL (also known as human secreted B7 homolog 2 (B7-H2), CD275, ICOSLG, and B7-related protein (B7RP), GenBank Accession No. NM_001283050. | |
III. Introduction | |
Host Cell: | CHO, Chinese Hamster Ovary |
Expressed gene: | ICOSL |
Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Synonym(s): | B7 homolog 2, CD275, ICOSL, ICOSLG, B7-related protein (B7RP), B7-H2 |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | F12k+10%FBS+500ug/ml Hygromycin |
Mycoplasma Testing: | Negative |
Storage: | Liquid nitrogen |
Application(s): | Ligand of ICOS&Binding Assay,FACS |
IV. Description of Host Cell Line | |
Organism: | Cricetulus griseus, hamster, Chinese |
Tissue: | Ovary |
Disease: | Hamster Chinese ovary |
Morphology: | Epitheloid cell |
Growth Properties: | Adherent |
Ⅴ. Representative Data | |
Figure 1.Recombinant CHO-cells constitutively expressing human ICOSL. | |