產(chǎn)品搜索
相關(guān)文章
- 甲基丙二酸血癥(MMA)標(biāo)準(zhǔn)品上新
- 【產(chǎn)品推介】TERT診斷標(biāo)準(zhǔn)品
- 你知道ATCC細(xì)胞如何解凍嗎?
- 有關(guān)腫瘤細(xì)胞的基因突變研究講解
- BCMA靶點(diǎn)藥物細(xì)胞篩選模型
- CD47/PD-(L)1 雙靶點(diǎn)細(xì)胞篩選模型簡介
- 從“腫瘤免疫療法”發(fā)展,看“單抗、CAR-T”任重而道遠(yuǎn)!
- 子宮內(nèi)膜癌精準(zhǔn)分子分型標(biāo)準(zhǔn)品,助力POLE基因檢測
- 耐藥ATCC細(xì)胞株如何構(gòu)建看完就會(huì)知道
- 腫瘤細(xì)胞的信息系統(tǒng)的改變特征大揭秘
聯(lián)系我們
電話:4008750250
號(hào)碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
藥靶細(xì)胞株 > kinase激酶細(xì)胞株 > CBP73255CSF3R S783fs/BaF3

- 詳細(xì)內(nèi)容
CBP73255 | |
I. Introduction | |
Cell Line Name: | CSF3R S783fs/BaF3 |
Host Cell: | Ba/F3 |
Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Application: | Anti-proliferation assay and PD assay |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS |
Mycoplasma Status: | Negative |
II.Background | |
CSF3R S783fs results in a change in the amino acid sequence of the Csf3r protein beginning at aa 783 of 836, likely resulting in premature truncation of the functional protein (UniProt.org). S783fs does not result in increased Stat3 activation (PMID: 23656643, PMID: 24403076), however, results in increased Src activation and transformation in cell culture (PMID: 23656643), and therefore, is predicted to result in a gain of Csf3r protein function. | |
III. Representative Data | |
1.WB of CSF3R S783fs/BaF3 | |
2. Anti-proliferation assay | |
Figure 2. Anti-proliferation assay of three reference compounds on the CSF3R S783fs/BaF3. |