EGFR C797S/BaF3 kinase細胞株-南京科佰生物科技有限公司

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聯(lián)系人：蔣經(jīng)理
電話：4008750250
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手機：18066071954
地址：南京市棲霞區(qū)緯地路9號
Email： zhangxiangwen@cobioer.com

CBP73167
I. Introduction
Cell Line Name：	EGFR C797S/BaF3
Host Cell:	Ba/F3
Stability:	16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium:	90% FBS+10% DMSO
Complete Culture Medium:	RPMI-1640+10%FBS
Mycoplasma Status:	Negative

II.Background
EGFR is the receptor for members of the EGF family and is a transmembrane glycoprotein that has tyrosine kinase activity.EGFR D770_N771insG results in the insertion of a glycine (G) in the protein kinase domain of the Egfr protein between amino acids 770 and 771 (UniProt.org). D770_N771insG has not been biochemically characterized, but is predicted to result in a gain of function based on the effect of other Egfr exon 20 insertions.

III. Representative Data
1. WB of EGFR C797S/BaF3
2. Sanger of EGFR C797S/BaF3
3. Anti-proliferation assay